Disease of myocardium. Several aetiology- no need for knowing them
-
DILATED CMP
-
AET: Viruses, Etoh, Ischaemia
-
Systolic CHF ie triad of DOE, Oorth, PND with crackles and pulm edema
-
Dx: Echo- dilated ventricles with poor contractility
-
CHF: BB, ACE, DU, stop aet, Transplant
-
HOCM
-
Echo- asymmetric septal wall thickening causing ventricular outlet obstruction
-
Aat: Generitcs, sarcomeeres. Mummurs of AS in young athletes with DOE, Syncope, Sudden cardiac death family hx
-
Rx: Avoid dehydration, cant exercise, BB and CCB (verapamil and ditiazem), Alcohol ablation or Myoectomy. AICD, eventually transplant
-
F/U: Screen first degree relatives
-
Concentric hypertrophy
-
Path: HTN
-
Diastolic CHF
-
Rx: Samilar to HOCM- avoid dehydration, BB=CCB, Transplant
-
RESTRICTIVE
-
Amyloid, sarcoid, haemochromatosis, cancers, fibroisis
-
Diastolic CF
-
Echo: Restrictive pattern
-
Aet workup: Neuropathy?- Amyloidosis. Pulmonary disease-> Sarcoidosis. Cirrhosis or DM ->haemochromatosis.
-
If suspect
-
amyloidosis- confirm with fat bad biopsy.
-
sarcoidosis: cardiac MRI and endomyocardial biopsy
-
Haemochromatosis: Ferritin elevated, genetics
-
Rx: Rx DIA CHF. BB=CCB. Gentle diuresis. Transplant. Rx underlying dx