Disease of myocardium. Several aetiology- no need for knowing them

 

  1. DILATED CMP
    1. AET: Viruses, Etoh, Ischaemia
    2. Systolic CHF ie triad of DOE, Oorth, PND with crackles and pulm edema
    3. Dx: Echo- dilated ventricles with poor contractility
    4. CHF: BB, ACE, DU, stop aet, Transplant
  2. HOCM
    1. Echo- asymmetric septal wall thickening causing ventricular outlet obstruction
    2. Aat: Generitcs, sarcomeeres. Mummurs of AS in young athletes with DOE, Syncope, Sudden cardiac death family hx
    3. Rx: Avoid dehydration, cant exercise, BB and CCB (verapamil and ditiazem), Alcohol ablation or Myoectomy. AICD, eventually transplant
    4. F/U: Screen first degree relatives
  3. Concentric hypertrophy
    1. Path: HTN
    2. Diastolic CHF
    3. Rx: Samilar to HOCM- avoid dehydration, BB=CCB, Transplant
  4. RESTRICTIVE
    1. Amyloid, sarcoid, haemochromatosis, cancers, fibroisis
    2. Diastolic CF
    3. Echo: Restrictive pattern
    4. Aet workup: Neuropathy?- Amyloidosis. Pulmonary disease-> Sarcoidosis. Cirrhosis or DM ->haemochromatosis.
    5. If suspect
      1. amyloidosis- confirm with fat bad biopsy.
      2. sarcoidosis: cardiac MRI and endomyocardial biopsy
      3. Haemochromatosis: Ferritin elevated, genetics
    6. Rx: Rx DIA CHF. BB=CCB. Gentle diuresis. Transplant. Rx underlying dx